Doyouknowwhat'sthematterwithhim??
Do you know what's the matter wh him? 这句话为什么不是 Do you know what the matter with him is? ？
先来看这个宾语从句：what is the matter with him? 在这里主语是what，而不是the matter 所以在宾语从句中的正确语序是Do you know what's the matter with him?